Biotinylated Human HLA-A*02:01&B2M&hTERT (ILAKFLHWL) Complex Protein (Monomer, MALS verified)
Biozol Catalog Number:
ABS-HLT-H82E5-200UG
Supplier Catalog Number:
HLT-H82E5-200ug
Alternative Catalog Number:
ABS-HLT-H82E5-200UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Biotin
hTERT (human Telomerase Reverse Transcriptase), the catalytic subunit of telomerase, maintains telomere length to drive tumor cells unlimited proliferation. It is highly expressed in ~8590% of cancers but silenced in most normal somatic cells. The peptide ILAKFLHWL (from hTERT residues 540548) acts as a tumorspecific antigen. It binds to MHC class I molecule HLAA0201 to form a surface complex on tumors, activating cytotoxic T lymphocytes (CTLs). The Human HLAA*0201 hTERT (ILAKFLHWL) complex protein is a complex of HLAA*0201 of the MHC Class I, B2M, and ILAKFLHWL peptide of the hTERT. - Proteine/Peptide
Immobilized Biotinylated Human HLA-A*02:01&B2M&hTERT (ILAKFLHWL) Complex Protein (Cat. No. HLT-H82E5) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Anti-HLA class I Antibody, Human IgG1 (W6/32) with a linear range of 0.1-2 ng/mL (QC tested).
Immobilized Biotinylated Human HLA-A*02:01&B2M&hTERT (ILAKFLHWL) Complex Protein (Cat. No. HLT-H82E5) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Anti-B2M Antibody, Human IgG1 with a linear range of 0.1-2 ng/mL (Routinely tested).
Biotinylated Human HLA-A*02:01&B2M&hTERT (ILAKFLHWL) Complex Protein on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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