Human IL-36 gamma / IL-1F9 Protein, Tag Free (MALS verified), Unconjugated, E. coli
Artikelnummer:
ABS-IL9-H5115-1MG
Hersteller Artikelnummer:
IL9-H5115-1mg
Alternativnummer:
ABS-IL9-H5115-1MG
Hersteller:
AcroBiosystems
Wirt:
E. coli
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
The IL36 subfamily of cytokines is the most diverse, including three agonists(IL36alpha, IL36beta, and IL36Γ), one antagonist(IL36Ra), one cognate receptor(IL36R) and one accessory protein(IL1RAcP). The receptor activation follows a twostep mechanism in that the agonist first binds to IL36R and the resulting binary complex recruits IL1RAcP. IL36gamma that binds to and signals through the IL36R which in turn activates NFkappaB and MAPK signaling pathways in target cells. Appropriately balanced IL36 signaling is a critical determinant of skin and lung health. - Proteine/Peptide
Human IL-36 gamma Protein, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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