Human Integrin alpha 6 beta 4 (ITGA6&ITGB4) Heterodimer Protein, His Tag&Tag Free (MALS verified), Unconjugated

Artikelnummer: ABS-IN4-H52W3-1MG
Artikelname: Human Integrin alpha 6 beta 4 (ITGA6&ITGB4) Heterodimer Protein, His Tag&Tag Free (MALS verified), Unconjugated
Artikelnummer: ABS-IN4-H52W3-1MG
Hersteller Artikelnummer: IN4-H52W3-1mg
Alternativnummer: ABS-IN4-H52W3-1MG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Konjugation: Unconjugated
Human integrin alpha(10)I domain as a recombinant protein to reveal its ligand binding specificity. In general, alpha(10)I did recognize collagen types IVI and laminin1 in a Mg(2+)dependent manner, whereas its binding to tenascin was only slightly better than to albumin. Alpha 10 beta 1 is a known collagenbinding I domain integrin, in addition to alpha1beta1, alpha2beta1 and alpha11beta1. GROGER found in the Nterminal domain of collagens I and III, is only weakly recognised by alpha10beta1, an important collagen receptor on chondrocytes, contrasting with the other collagenbinding integrins. - Proteine/Peptide
Molekulargewicht: 116.8 kDa | 81.8 kDa
Tag: C-10*His | Native
NCBI: 23229
Puffer: 50 mM Tris, 150 mM NaCl, 0.2 M Arginine, pH7.5
Reinheit: 95%
Formulierung: Powder
Target-Kategorie: Integrin alpha 6 beta 4
Immobilized Human ITGA6&ITGB4 Heterodimer Protein, His Tag&Tag Free (Cat. No. IN4-H52W3) at 5 µg/mL (100 µL/well) can bind Human Laminin 511 Protein, premium grade (Cat. No. LA8-H5283) with a linear range of 0.8-13 ng/mL (QC tested).
Immobilized Human Laminin 511 Protein, premium grade (Cat. No. LA8-H5283) at 5 µg/mL (100 µL/well) can bind Human ITGA6&ITGB4 Heterodimer Protein, His Tag&Tag Free (Cat. No. IN4-H52W3) with a linear range of 0.01-0.156 µg/mL (Routinely tested).
Human ITGA6&ITGB4 Heterodimer Protein, His Tag&Tag Free on SDS-PAGE under non-reducing (NR) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.