Human Integrin alpha 6 beta 4 (ITGA6&ITGB4) Heterodimer Protein, His Tag&Tag Free (MALS verified), Unconjugated

Product Overview

• Article Name: Human Integrin alpha 6 beta 4 (ITGA6&ITGB4) Heterodimer Protein, His Tag&Tag Free (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-IN4-H52W3-1MG
• Supplier Catalog Number: IN4-H52W3-1mg
• Alternative Catalog Number: ABS-IN4-H52W3-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Human integrin alpha(10)I domain as a recombinant protein to reveal its ligand binding specificity. In general, alpha(10)I did recognize collagen types IVI and laminin1 in a Mg(2+)dependent manner, whereas its binding to tenascin was only slightly better than to albumin. Alpha 10 beta 1 is a known collagenbinding I domain integrin, in addition to alpha1beta1, alpha2beta1 and alpha11beta1. GROGER found in the Nterminal domain of collagens I and III, is only weakly recognised by alpha10beta1, an important collagen receptor on chondrocytes, contrasting with the other collagenbinding integrins. - Proteine/Peptide

Product Properties

• Molecular Weight: 116.8 kDa | 81.8 kDa
• Tag: C-10*His | Native
• NCBI: 23229
• Buffer: 50 mM Tris, 150 mM NaCl, 0.2 M Arginine, pH7.5
• Purity: 95%
• Form: Powder
• Target: Integrin alpha 6 beta 4

Images

Immobilized Human ITGA6&ITGB4 Heterodimer Protein, His Tag&Tag Free (Cat. No. IN4-H52W3) at 5 µg/mL (100 µL/well) can bind Human Laminin 511 Protein, premium grade (Cat. No. LA8-H5283) with a linear range of 0.8-13 ng/mL (QC tested).

Immobilized Human Laminin 511 Protein, premium grade (Cat. No. LA8-H5283) at 5 µg/mL (100 µL/well) can bind Human ITGA6&ITGB4 Heterodimer Protein, His Tag&Tag Free (Cat. No. IN4-H52W3) with a linear range of 0.01-0.156 µg/mL (Routinely tested).

Human ITGA6&ITGB4 Heterodimer Protein, His Tag&Tag Free on SDS-PAGE under non-reducing (NR) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.