Mouse Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer Protein, Flag Tag&Tag Free, Unconjugated

Produktübersicht

• Artikelname: Mouse Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer Protein, Flag Tag&Tag Free, Unconjugated
• Artikelnummer: ABS-IT1-M53D3-1MG
• Hersteller Artikelnummer: IT1-M53D3-1mg
• Alternativnummer: ABS-IT1-M53D3-1MG
• Hersteller: AcroBiosystems
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Mouse
• Konjugation: Unconjugated

Produktbeschreibung

Integrin alpha V beta 1 (alphaVbeta1) is a widely expressed adhesion receptor formed by the noncovalent association of the alphaV and beta1 (CD29) subunits. Its activity is regulated by a conformational shift from a folded, lowaffinity state to an extended, highaffinity state, a process triggered by divalent cations and intracellular signaling. As a canonical RGDbinding integrin, it interacts with ligands including vitronectin, fibronectin, and osteopontin. This interaction is central to its role in mediating cell migration, where its modest binding affinity enables the cyclic attachment and detachment necessary for cell movement. Furthermore, alphaVbeta1 is implicated in cellular differentiation and is coopted by pathogens, such as footandmouth disease virus, for host cell entry. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 112.3 kDa (ITGAV) & 83.5 kDa (ITGB1)
• Tag: C-Flag | Native
• NCBI: 032428
• Puffer: 50 mM Tris, 150 mM NaCl, pH8.0
• Reinheit: 90%
• Formulierung: Powder
• Target-Kategorie: Integrin alpha V beta 1

Bilder

Mouse ITGAV&ITGB1 Heterodimer Protein, Flag Tag&Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.