Mouse Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer Protein, Flag Tag&Tag Free, Unconjugated

Product Overview

• Article Name: Mouse Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer Protein, Flag Tag&Tag Free, Unconjugated
• Biozol Catalog Number: ABS-IT1-M53D3-1MG
• Supplier Catalog Number: IT1-M53D3-1mg
• Alternative Catalog Number: ABS-IT1-M53D3-1MG
• Manufacturer: AcroBiosystems
• Category: Proteine/Peptide
• Species Reactivity: Mouse
• Conjugation: Unconjugated

Product Description

Integrin alpha V beta 1 (alphaVbeta1) is a widely expressed adhesion receptor formed by the noncovalent association of the alphaV and beta1 (CD29) subunits. Its activity is regulated by a conformational shift from a folded, lowaffinity state to an extended, highaffinity state, a process triggered by divalent cations and intracellular signaling. As a canonical RGDbinding integrin, it interacts with ligands including vitronectin, fibronectin, and osteopontin. This interaction is central to its role in mediating cell migration, where its modest binding affinity enables the cyclic attachment and detachment necessary for cell movement. Furthermore, alphaVbeta1 is implicated in cellular differentiation and is coopted by pathogens, such as footandmouth disease virus, for host cell entry. - Proteine/Peptide

Product Properties

• Molecular Weight: 112.3 kDa (ITGAV) & 83.5 kDa (ITGB1)
• Tag: C-Flag | Native
• NCBI: 032428
• Buffer: 50 mM Tris, 150 mM NaCl, pH8.0
• Purity: 90%
• Form: Powder
• Target: Integrin alpha V beta 1

Images

Mouse ITGAV&ITGB1 Heterodimer Protein, Flag Tag&Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.