Biotinylated Human Langerin Protein, Avitag(TM),His Tag
Artikelnummer:
ABS-LAN-H82Q3-200UG
Hersteller Artikelnummer:
LAN-H82Q3-200ug
Alternativnummer:
ABS-LAN-H82Q3-200UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Biotin
Langerin (CD207) is a crucial Ctype lectin receptor (CLR) primarily expressed by Langerhans cells (LCs) in the epidermis. It functions as a pattern recognition receptor (PRR), utilizing its extracellular domain to specifically bind carbohydrate structures on pathogens (e.g., mannose, fucose). Uniquely associated with Birbeck granules, Langerin mediates efficient antigen internalization and processing, thereby enabling LCs to initiate adaptive immune responses and restrict certain infections. Its distinct expression also serves as a key diagnostic marker for Langerhans Cell Histiocytosis (LCH). - Proteine/Peptide
Biotinylated Human Langerin Protein, Avitag,His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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