Biotinylated Human Langerin Protein, Avitag(TM),His Tag

Product Overview

• Article Name: Biotinylated Human Langerin Protein, Avitag(TM),His Tag
• Biozol Catalog Number: ABS-LAN-H82Q3-200UG
• Supplier Catalog Number: LAN-H82Q3-200ug
• Alternative Catalog Number: ABS-LAN-H82Q3-200UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

Langerin (CD207) is a crucial Ctype lectin receptor (CLR) primarily expressed by Langerhans cells (LCs) in the epidermis. It functions as a pattern recognition receptor (PRR), utilizing its extracellular domain to specifically bind carbohydrate structures on pathogens (e.g., mannose, fucose). Uniquely associated with Birbeck granules, Langerin mediates efficient antigen internalization and processing, thereby enabling LCs to initiate adaptive immune responses and restrict certain infections. Its distinct expression also serves as a key diagnostic marker for Langerhans Cell Histiocytosis (LCH). - Proteine/Peptide

Product Properties

• Molecular Weight: 33.4 kDa
• Tag: N-Avi & N-10*His
• NCBI: 9
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: Langerin

Images

Biotinylated Human Langerin Protein, Avitag,His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.