Biotinylated Human LGR5 / GPR49 (22-561) Protein, His,Avitag(TM)
Artikelnummer:
ABS-LG5-H82E4-25UG
Hersteller Artikelnummer:
LG5-H82E4-25ug
Alternativnummer:
ABS-LG5-H82E4-25UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Biotin
LGR5 (also known as GPR49) is a seventransmembrane protein of the class A Rhodopsinlike family of GPCRs. LGR5 and LGR4 bind the Rspondins with high affinity and mediate the potentiation of Wnt/betacatenin signaling by enhancing Wntinduced LRP6 phosphorylation. The LGR5/RSPO complex could promote Wnt signalling via the neutralization of two transmembrane E3 ligases, RNF43 and ZNRF3. - Proteine/Peptide
Immobilized Human R-Spondin 3 (22-146), His Tag (Cat. No. RS6-H5222) at 5 µg/mL (100 µL/well) can bind Biotinylated Human LGR5 (22-561) Protein, His,Avitag (Cat. No. LG5-H82E4) with a linear range of 2-78 ng/mL (QC tested).
Immobilized Human R-Spondin 3 Protein, Fc Tag (Cat. No. RS3-H5253) at 5 µg/mL (100 µL/well) can bind Biotinylated Human LGR5 (22-561) Protein, His,Avitag (Cat. No. LG5-H82E4) with a linear range of 0.2-5 ng/mL (Routinely tested).
Biotinylated Human LGR5 (22-561) Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten