Biotinylated Human LGR5 / GPR49 (22-561) Protein, His,Avitag(TM)
Artikelnummer:
ABS-LG5-H82E4-25UG
Hersteller Artikelnummer:
LG5-H82E4-25ug
Alternativnummer:
ABS-LG5-H82E4-25UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Biotin
LGR5 (also known as GPR49) is a seventransmembrane protein of the class A Rhodopsinlike family of GPCRs. LGR5 and LGR4 bind the Rspondins with high affinity and mediate the potentiation of Wnt/betacatenin signaling by enhancing Wntinduced LRP6 phosphorylation. The LGR5/RSPO complex could promote Wnt signalling via the neutralization of two transmembrane E3 ligases, RNF43 and ZNRF3. - Proteine/Peptide
