Biotinylated Human LGR5 / GPR49 (22-561) Protein, His,Avitag(TM)

Product Overview

• Article Name: Biotinylated Human LGR5 / GPR49 (22-561) Protein, His,Avitag(TM)
• Biozol Catalog Number: ABS-LG5-H82E4-25UG
• Supplier Catalog Number: LG5-H82E4-25ug
• Alternative Catalog Number: ABS-LG5-H82E4-25UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

LGR5 (also known as GPR49) is a seventransmembrane protein of the class A Rhodopsinlike family of GPCRs. LGR5 and LGR4 bind the Rspondins with high affinity and mediate the potentiation of Wnt/betacatenin signaling by enhancing Wntinduced LRP6 phosphorylation. The LGR5/RSPO complex could promote Wnt signalling via the neutralization of two transmembrane E3 ligases, RNF43 and ZNRF3. - Proteine/Peptide

Product Properties

• Molecular Weight: 64.1 kDa
• Tag: C-10*His & C-Avi
• NCBI: 75473
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: LGR5

Images

Immobilized Human R-Spondin 3 (22-146), His Tag (Cat. No. RS6-H5222) at 5 µg/mL (100 µL/well) can bind Biotinylated Human LGR5 (22-561) Protein, His,Avitag (Cat. No. LG5-H82E4) with a linear range of 2-78 ng/mL (QC tested).

Immobilized Human R-Spondin 3 Protein, Fc Tag (Cat. No. RS3-H5253) at 5 µg/mL (100 µL/well) can bind Biotinylated Human LGR5 (22-561) Protein, His,Avitag (Cat. No. LG5-H82E4) with a linear range of 0.2-5 ng/mL (Routinely tested).

Biotinylated Human LGR5 (22-561) Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.