Human LRP-6 (20-630) Protein, Mouse IgG2a Fc Tag, Unconjugated

Produktübersicht

• Artikelname: Human LRP-6 (20-630) Protein, Mouse IgG2a Fc Tag, Unconjugated
• Artikelnummer: ABS-LR6-H5253-1MG
• Hersteller Artikelnummer: LR6-H5253-1mg
• Alternativnummer: ABS-LR6-H5253-1MG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

LRP6 is a transmembrane lowdensity lipoprotein receptor that shares a similar structure with LRP5. Lowdensity lipoprotein receptorrelated protein 6 is a key component of the LRP5/LRP6/Frizzled coreceptor group that is involved in canonical Wnt pathway. The Wntinduced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3Bcomplex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3mediated phosphorylation and destruction of betacatenin. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 95.8 kDa
• Tag: C-mFc(mIgG2a)
• NCBI: 75581
• Puffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Expression System: Ala 20 - Pro 630
• Reinheit: 90%
• Formulierung: Powder
• Target-Kategorie: LRP-6

Bilder

LR6-H5253-1mg