Human LRP-6 (20-630) Protein, Mouse IgG2a Fc Tag, Unconjugated

Product Overview

• Article Name: Human LRP-6 (20-630) Protein, Mouse IgG2a Fc Tag, Unconjugated
• Biozol Catalog Number: ABS-LR6-H5253-1MG
• Supplier Catalog Number: LR6-H5253-1mg
• Alternative Catalog Number: ABS-LR6-H5253-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

LRP6 is a transmembrane lowdensity lipoprotein receptor that shares a similar structure with LRP5. Lowdensity lipoprotein receptorrelated protein 6 is a key component of the LRP5/LRP6/Frizzled coreceptor group that is involved in canonical Wnt pathway. The Wntinduced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3Bcomplex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3mediated phosphorylation and destruction of betacatenin. - Proteine/Peptide

Product Properties

• Molecular Weight: 95.8 kDa
• Tag: C-mFc(mIgG2a)
• NCBI: 75581
• Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Expression System: Ala 20 - Pro 630
• Purity: 90%
• Form: Powder
• Target: LRP-6

Images

LR6-H5253-1mg