Human LRP-6 (20-630) Protein, Mouse IgG2a Fc Tag, Unconjugated

Product Overview

• Article Name: Human LRP-6 (20-630) Protein, Mouse IgG2a Fc Tag, Unconjugated
• Biozol Catalog Number: ABS-LR6-H5253-1MG
• Supplier Catalog Number: LR6-H5253-1mg
• Alternative Catalog Number: ABS-LR6-H5253-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

LRP6 is a transmembrane lowdensity lipoprotein receptor that shares a similar structure with LRP5. Lowdensity lipoprotein receptorrelated protein 6 is a key component of the LRP5/LRP6/Frizzled coreceptor group that is involved in canonical Wnt pathway. The Wntinduced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3Bcomplex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3mediated phosphorylation and destruction of betacatenin. - Proteine/Peptide

Product Properties

• Molecular Weight: 95.8 kDa
• Tag: C-mFc(mIgG2a)
• NCBI: 75581
• Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Purity: 90%
• Form: Powder
• Target: LRP-6

Images

Immobilized Mouse Dkk-1, His Tag (Cat. No. DK1-M52H6) at 5 µg/mL (100 µL/well) can bind Human LRP-6 (20-630), Mouse IgG2a Fc Tag (Cat. No. LR6-H5253) with a linear range of 10-78 ng/mL (QC tested).

Immobilized Human R-Spondin 1, His Tag (Cat. No. RS1-H4221) at 5 µg/mL (100 µL/well) can bind Human LRP-6 (20-630), Mouse IgG2a Fc Tag (Cat. No. LR6-H5253) with a linear range of 1-20 ng/mL (Routinely tested).

Human LRP-6 (20-630), Mouse IgG2a Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.