Mouse LY75 / CD205 Protein, His Tag (MALS verified), Unconjugated, Human

Produktübersicht

• Artikelname: Mouse LY75 / CD205 Protein, His Tag (MALS verified), Unconjugated, Human
• Artikelnummer: ABS-LY5-M52H5-100UG
• Hersteller Artikelnummer: LY5-M52H5-100ug
• Alternativnummer: ABS-LY5-M52H5-100UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Mouse
• Konjugation: Unconjugated

Produktbeschreibung

lymphocyte antigen 75 (Ly 75, also known as CD205, CLEC13B, GP200MR6 and DEC205, is a type I transmembrane protein that is primarily expressed on dendritic cells and thymic epithelial cells. LY75 functions as an endocytic receptor for antigens. MEN1309/OBT076, the first antibody drug targeting CD205, has shown strong preclinical antitumor activity in lymphoma. After being verified as a single drug in vivo, the antibodydrug conjugate has a synergistic effect with the BCL2 inhibitor Venetoclax and the anticd20 monoclonal antibody rituximab. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 190.0 kDa
• Tag: C-10*His
• NCBI: 60767
• Puffer: PBS, pH7.4
• Reinheit: 90%
• Formulierung: Powder
• Target-Kategorie: LY75

Bilder

Mouse LY75, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.