Mouse LY75 / CD205 Protein, His Tag (MALS verified), Unconjugated, Human

Product Overview

• Article Name: Mouse LY75 / CD205 Protein, His Tag (MALS verified), Unconjugated, Human
• Biozol Catalog Number: ABS-LY5-M52H5-100UG
• Supplier Catalog Number: LY5-M52H5-100ug
• Alternative Catalog Number: ABS-LY5-M52H5-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Mouse
• Conjugation: Unconjugated

Product Description

lymphocyte antigen 75 (Ly 75, also known as CD205, CLEC13B, GP200MR6 and DEC205, is a type I transmembrane protein that is primarily expressed on dendritic cells and thymic epithelial cells. LY75 functions as an endocytic receptor for antigens. MEN1309/OBT076, the first antibody drug targeting CD205, has shown strong preclinical antitumor activity in lymphoma. After being verified as a single drug in vivo, the antibodydrug conjugate has a synergistic effect with the BCL2 inhibitor Venetoclax and the anticd20 monoclonal antibody rituximab. - Proteine/Peptide

Product Properties

• Molecular Weight: 190.0 kDa
• Tag: C-10*His
• NCBI: 60767
• Buffer: PBS, pH7.4
• Expression System: Ser 28 - Asp 1667
• Purity: 90%
• Form: Powder
• Target: LY75

Images

LY5-M52H5-100ug