Biotinylated Cynomolgus Mucin-1 / MUC-1 Protein, His,Avitag(TM) (MALS verified), Human
Artikelnummer:
ABS-MU1-C82E3-200UG
Hersteller Artikelnummer:
MU1-C82E3-200ug
Alternativnummer:
ABS-MU1-C82E3-200UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Monkey
Konjugation:
Biotin
This gene encodes a membranebound protein that is a member of the mucin family. Mucins are Oglycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The Nterminal alpha subunit functions in celladhesion and the Cterminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants - Proteine/Peptide
