Biotinylated Cynomolgus Mucin-1 / MUC-1 Protein, His,Avitag(TM) (MALS verified), Human
Biozol Catalog Number:
ABS-MU1-C82E3-200UG
Supplier Catalog Number:
MU1-C82E3-200ug
Alternative Catalog Number:
ABS-MU1-C82E3-200UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Monkey
Conjugation:
Biotin
This gene encodes a membranebound protein that is a member of the mucin family. Mucins are Oglycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The Nterminal alpha subunit functions in celladhesion and the Cterminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants - Proteine/Peptide
