Human NKG2A&CD94 Protein, Mouse IgG2a Fc Tag (MALS verified), Unconjugated
Artikelnummer:
ABS-NC4-H5253-1MG
Hersteller Artikelnummer:
NC4-H5253-1mg
Alternativnummer:
ABS-NC4-H5253-1MG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
CD94 plays a role as a receptor for the recognition of MHC class I HLAE molecules by NK cells and some cytotoxic Tcells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of Ctype lectinlike receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)E on target cells. - Proteine/Peptide