Human NKG2A&CD94 Protein, Mouse IgG2a Fc Tag (MALS verified), Unconjugated

Product Overview

• Article Name: Human NKG2A&CD94 Protein, Mouse IgG2a Fc Tag (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-NC4-H5253-1MG
• Supplier Catalog Number: NC4-H5253-1mg
• Alternative Catalog Number: ABS-NC4-H5253-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

CD94 plays a role as a receptor for the recognition of MHC class I HLAE molecules by NK cells and some cytotoxic Tcells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of Ctype lectinlike receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)E on target cells. - Proteine/Peptide

Product Properties

• Molecular Weight: 55.5 kDa
• Tag: C-mFc(mIgG2a)
• NCBI: 26715
• Buffer: 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
• Purity: 95%
• Form: Powder
• Target: NKG2A & CD94

Images

Immobilized Human NKG2A&CD94, Mouse IgG2a Fc Tag (Cat. No. NC4-H5253) at 2 µg/mL (100 µL/well) can bind Monoclonal Anti-NKG2A (Z270), Human IgG1 with a linear range of 0.2-8 ng/mL (QC tested).

Immobilized Human NKG2A&CD94, Mouse IgG2a Fc Tag (Cat. No. NC4-H5253) at 5 µg/mL (100 µL/well) can bind various dilution ratio of HLA-E*01:03 HLA-A leader3-11Tetramer-VMAPRTLVL-PE (Routinely tested).

Human NKG2A&CD94, Mouse IgG2a Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.