Human Nectin-4 Protein, Fc Tag (MALS verified), Unconjugated
Artikelnummer:
ABS-NE4-H5255-100UG
Hersteller Artikelnummer:
NE4-H5255-100ug
Alternativnummer:
ABS-NE4-H5255-100UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Nectin4 (gene name PVRL4, poliovirus receptorlike 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin4 is a tumorassociated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues. - Proteine/Peptide
Immobilized Human Nectin-4, Fc Tag (Cat. No. NE4-H5255) at 1 µg/mL (100 µL/well) can bind Enfortumab with a linear range of 0.1-2 ng/mL (QC tested).
Immobilized Human Nectin-4, Fc Tag (Cat. No. NE4-H5255) at 5 µg/mL (100 µL/well) can bind Human Nectin-1, His Tag (Cat. No. PV1-H5223) with a linear range of 0.2-3 µg/mL (QC tested).
Human Nectin-4, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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