Human Nectin-4 Protein, Fc Tag (MALS verified), Unconjugated

Product Overview

• Article Name: Human Nectin-4 Protein, Fc Tag (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-NE4-H5255-100UG
• Supplier Catalog Number: NE4-H5255-100ug
• Alternative Catalog Number: ABS-NE4-H5255-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Nectin4 (gene name PVRL4, poliovirus receptorlike 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin4 is a tumorassociated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues. - Proteine/Peptide

Product Properties

• Molecular Weight: 60.5 kDa
• Tag: C-Fc
• NCBI: 96
• Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Purity: 95%
• Form: Powder
• Target: Nectin-4

Images

NE4-H5255-100ug

Immobilized Human Nectin-4, Fc Tag (Cat. No. NE4-H5255) at 1 µg/mL (100 µL/well) can bind Enfortumab with a linear range of 0.1-2 ng/mL (QC tested).

Immobilized Human Nectin-4, Fc Tag (Cat. No. NE4-H5255) at 5 µg/mL (100 µL/well) can bind Human Nectin-1, His Tag (Cat. No. PV1-H5223) with a linear range of 0.2-3 µg/mL (QC tested).

Human Nectin-4, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.