Human Nectin-4 Protein, Fc Tag (MALS verified), Unconjugated
Biozol Catalog Number:
ABS-NE4-H5255-100UG
Supplier Catalog Number:
NE4-H5255-100ug
Alternative Catalog Number:
ABS-NE4-H5255-100UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Nectin4 (gene name PVRL4, poliovirus receptorlike 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin4 is a tumorassociated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues. - Proteine/Peptide
