Biotinylated Human PSGL-1 / CD162 Protein, His,Avitag(TM)

Produktübersicht

• Artikelname: Biotinylated Human PSGL-1 / CD162 Protein, His,Avitag(TM)
• Artikelnummer: ABS-PS1-H82E4-200UG
• Hersteller Artikelnummer: PS1-H82E4-200ug
• Alternativnummer: ABS-PS1-H82E4-200UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Biotin

Produktbeschreibung

Pselectin glycoprotein ligand 1 (PSGL1) is also known as Selectin P ligand (SELPLG), CD antigen CD162. PSGL1 is disulfidelinked homodimer which is the high affinitycounterreceptor for Pselectin on expressed on activated endothelial cells and platelets. PSGL1 / SELPLG interacts with P, E and Lselectins, through their lectin/EGF domains, is required for promoting recruitment and rolling of leukocytes. These interactions require sialyl Lewis X glycan modification but there is a differing dependence for tyrosine sulfations. Dimerization appears not to be required for Pselectin/SELP binding. PSGL1 can interact with SNX20, MSN and SYK. PSGL1 / SELPLG mediate the activation of SYK by SELPLG. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 32.4 kDa
• Tag: C-10*His & C-Avi
• NCBI: 14242
• Puffer: PBS, pH7.4
• Reinheit: 90%
• Formulierung: Powder
• Target-Kategorie: PSGL-1

Bilder

Biotinylated Human PSGL-1, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.