Biotinylated Human PSGL-1 / CD162 Protein, His,Avitag(TM)

Product Overview

• Article Name: Biotinylated Human PSGL-1 / CD162 Protein, His,Avitag(TM)
• Biozol Catalog Number: ABS-PS1-H82E4-200UG
• Supplier Catalog Number: PS1-H82E4-200ug
• Alternative Catalog Number: ABS-PS1-H82E4-200UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

Pselectin glycoprotein ligand 1 (PSGL1) is also known as Selectin P ligand (SELPLG), CD antigen CD162. PSGL1 is disulfidelinked homodimer which is the high affinitycounterreceptor for Pselectin on expressed on activated endothelial cells and platelets. PSGL1 / SELPLG interacts with P, E and Lselectins, through their lectin/EGF domains, is required for promoting recruitment and rolling of leukocytes. These interactions require sialyl Lewis X glycan modification but there is a differing dependence for tyrosine sulfations. Dimerization appears not to be required for Pselectin/SELP binding. PSGL1 can interact with SNX20, MSN and SYK. PSGL1 / SELPLG mediate the activation of SYK by SELPLG. - Proteine/Peptide

Product Properties

• Molecular Weight: 32.4 kDa
• Tag: C-10*His & C-Avi
• NCBI: 14242
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: PSGL-1

Images

Biotinylated Human PSGL-1, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.