Human R-Spondin 1 / RSPO1 Protein, His Tag, Unconjugated
Artikelnummer:
ABS-RS1-H4221-1MG
Hersteller Artikelnummer:
RS1-H4221-1mg
Alternativnummer:
ABS-RS1-H4221-1MG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Rspondin1 is also known as Roof platespecific Spondin 1 (RSPO1) and cysteinerich and single thrombospondin domain containing protein 3 (Cristin 3), which is a secreted protein which belongs to the RSpondin family and encodes a secreted activator protein with two cysteinrich, furinlike domains and one thrombospondin type 1 domain. All Rspondins regulate Wnt/betacatenin signaling, but have distinct expression patterns. Like other RSpondins, RSpondin1 contains two adjacent cysteinerich furinlike domains (aa 34135) with one potential Nglycosylation site, followed by a thrombospondin (TSP1) motif (aa 147207) and a region rich in basic residues (aa 211263). Only the furinlike domains are needed for betacatenin stabilization. A putative nuclear localization signal at the Cterminus may allow some expression in the nucleus. - Proteine/Peptide
Immobilized Human R-Spondin 1, His Tag (Cat. No. RS1-H4221) at 5 µg/mL (100 µL/well) can bind Human SCARB2, Fc Tag (Cat. No. SC2-H5250) with a linear range of 0.02-1.25 µg/mL (QC tested).
Immobilized Human R-Spondin 1, His Tag (Cat. No. RS1-H4221) at 5 µg/mL (100 µL/well) can bind Biotinylated Human CD36, His,Avitag (Cat. No. CD6-H82E9) with a linear range of 0.01-1.25 µg/mL (Routinely tested).
Human R-Spondin 1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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