Human R-Spondin 1 / RSPO1 Protein, His Tag, Unconjugated

Product Overview

• Article Name: Human R-Spondin 1 / RSPO1 Protein, His Tag, Unconjugated
• Biozol Catalog Number: ABS-RS1-H4221-1MG
• Supplier Catalog Number: RS1-H4221-1mg
• Alternative Catalog Number: ABS-RS1-H4221-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Rspondin1 is also known as Roof platespecific Spondin 1 (RSPO1) and cysteinerich and single thrombospondin domain containing protein 3 (Cristin 3), which is a secreted protein which belongs to the RSpondin family and encodes a secreted activator protein with two cysteinrich, furinlike domains and one thrombospondin type 1 domain. All Rspondins regulate Wnt/betacatenin signaling, but have distinct expression patterns. Like other RSpondins, RSpondin1 contains two adjacent cysteinerich furinlike domains (aa 34135) with one potential Nglycosylation site, followed by a thrombospondin (TSP1) motif (aa 147207) and a region rich in basic residues (aa 211263). Only the furinlike domains are needed for betacatenin stabilization. A putative nuclear localization signal at the Cterminus may allow some expression in the nucleus. - Proteine/Peptide

Product Properties

• Molecular Weight: 28.7 kDa
• Tag: C-10*His
• NCBI: 2
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: R-Spondin 1

Images

Immobilized Human R-Spondin 1, His Tag (Cat. No. RS1-H4221) at 5 µg/mL (100 µL/well) can bind Human SCARB2, Fc Tag (Cat. No. SC2-H5250) with a linear range of 0.02-1.25 µg/mL (QC tested).

Immobilized Human R-Spondin 1, His Tag (Cat. No. RS1-H4221) at 5 µg/mL (100 µL/well) can bind Biotinylated Human CD36, His,Avitag (Cat. No. CD6-H82E9) with a linear range of 0.01-1.25 µg/mL (Routinely tested).

Human R-Spondin 1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.