Human TREM2 (19-157) Protein, Fc Tag, Unconjugated
Artikelnummer:
ABS-TR2-H5258-100UG
Hersteller Artikelnummer:
TR2-H5258-100ug
Alternativnummer:
ABS-TR2-H5258-100UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Triggering Receptor Expressed on Myeloid cells 2 (TREM2) is a pivotal cellsurface receptor primarily found on microglia in the brain and macrophages in peripheral tissues. Acting as a lipid and amyloidbeta sensor, it signals through the adapter protein DAP12 to regulate immune responses, cell survival, and phagocytosis. In neurobiology, TREM2 is a major focus because its dysfunction is strongly linked to Alzheimers disease progression and impaired clearance of neurotoxic plaques. - Proteine/Peptide