Human TREM2 (19-157) Protein, Fc Tag, Unconjugated

Product Overview

• Article Name: Human TREM2 (19-157) Protein, Fc Tag, Unconjugated
• Biozol Catalog Number: ABS-TR2-H5258-100UG
• Supplier Catalog Number: TR2-H5258-100ug
• Alternative Catalog Number: ABS-TR2-H5258-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Triggering Receptor Expressed on Myeloid cells 2 (TREM2) is a pivotal cellsurface receptor primarily found on microglia in the brain and macrophages in peripheral tissues. Acting as a lipid and amyloidbeta sensor, it signals through the adapter protein DAP12 to regulate immune responses, cell survival, and phagocytosis. In neurobiology, TREM2 is a major focus because its dysfunction is strongly linked to Alzheimers disease progression and impaired clearance of neurotoxic plaques. - Proteine/Peptide

Product Properties

• Molecular Weight: 42.1 kDa
• Tag: C-Fc
• NCBI: 9
• Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
• Purity: 90%
• Form: Powder
• Target: TREM2