Anti-Trastuzumab Antibody (AY1b) (recommended for PK/PD), Unconjugated, Human

Artikelnummer: ABS-TRB-Y1B-1MG
Artikelname: Anti-Trastuzumab Antibody (AY1b) (recommended for PK/PD), Unconjugated, Human
Artikelnummer: ABS-TRB-Y1B-1MG
Hersteller Artikelnummer: TRB-Y1b-1mg
Alternativnummer: ABS-TRB-Y1B-1MG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Antikörper
Spezies Reaktivität: Mouse
Konjugation: Unconjugated
Trastuzumab, is a monoclonal antibody used to treat breast cancer. Specifically it is used for breast cancer that is HER2 receptor positive. Trastuzumab works by binding to the HER2 receptor and slowing down cell duplication. Trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cellbased assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein. - Antikörper
Tag: Mouse IgG1 | Mouse Kappa
Puffer: Tris with Glycine, Arginine and NaCl, pH7.5
Reinheit: 0.95
Formulierung: Powder
Target-Kategorie: Trastuzumab
Immobilized Trastuzumab at 1 µg/mL (100 µL/well) can bind Anti-Trastuzumab Antibody (AY1b) (Cat. No. TRB-Y1b) with a linear range of 0.4-6 ng/mL (QC tested).
Immobilized Anti-Trastuzumab Antibody (AY1b) (Cat. No. TRB-Y1b) at 2µg/mL, add increasing concentrations of Trastuzumab in the 10% human serum and then add Biotinylated Anti-Trastuzumab Antibodies at 2µg/mL. Detection was performed using HRP-conjugated streptavidin with sensitivity of 48 ng/mL (QC tested).
Anti-Trastuzumab Antibody (AY1b) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 0.95.
TRB-Y1b-1mg