Anti-Trastuzumab Antibody (AY1b) (recommended for PK/PD), Unconjugated, Human

Product Overview

• Article Name: Anti-Trastuzumab Antibody (AY1b) (recommended for PK/PD), Unconjugated, Human
• Biozol Catalog Number: ABS-TRB-Y1B-1MG
• Supplier Catalog Number: TRB-Y1b-1mg
• Alternative Catalog Number: ABS-TRB-Y1B-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Antikörper
• Species Reactivity: Mouse
• Conjugation: Unconjugated

Product Description

Trastuzumab, is a monoclonal antibody used to treat breast cancer. Specifically it is used for breast cancer that is HER2 receptor positive. Trastuzumab works by binding to the HER2 receptor and slowing down cell duplication. Trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cellbased assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein. - Antikörper

Product Properties

• Tag: Mouse IgG1 | Mouse Kappa
• Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Purity: 0.95
• Form: Powder
• Target: Trastuzumab

Images

Immobilized Trastuzumab at 1 µg/mL (100 µL/well) can bind Anti-Trastuzumab Antibody (AY1b) (Cat. No. TRB-Y1b) with a linear range of 0.4-6 ng/mL (QC tested).

Immobilized Anti-Trastuzumab Antibody (AY1b) (Cat. No. TRB-Y1b) at 2µg/mL, add increasing concentrations of Trastuzumab in the 10% human serum and then add Biotinylated Anti-Trastuzumab Antibodies at 2µg/mL. Detection was performed using HRP-conjugated streptavidin with sensitivity of 48 ng/mL (QC tested).

Anti-Trastuzumab Antibody (AY1b) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 0.95.

TRB-Y1b-1mg