Human USP1 & UAF1 Protein, GST Tag&Strep II Tag, Unconjugated, Insect 100 ug

Produktübersicht

• Artikelname: Human USP1 & UAF1 Protein, GST Tag&Strep II Tag, Unconjugated, Insect 100 ug
• Artikelnummer: ABS-US1-H85W3-100UG
• Hersteller Artikelnummer: US1-H85W3-100ug
• Alternativnummer: ABS-US1-H85W3-100UG
• Hersteller: AcroBiosystems
• Wirt: Insect
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

USP1 (ubiquitin-specific protease 1) is a deubiquitinating enzyme crucial for DNA damage repair, cell cycle regulation, and protein homeostasis. Its catalytic efficiency is markedly enhanced by UAF1 (USP1-associated factor 1), a cofactor that stabilizes USP1 and directs it to nuclear substrates. Together, the USP1-UAF1 complex removes ubiquitin from key proteins such as PCNA and FANCD2, maintaining genomic stability and influencing cancer development, making it a potential therapeutic target in oncology. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 114.1 kDa & 77.8 kDa
• Tag: N-GST | C-Strep II
• NCBI: 94782
• Puffer: 50 mM Tris, 150 mM NaCI, pH7.5
• Reinheit: 95%
• Formulierung: Liquid
• Target-Kategorie: USP1 & UAF1

Bilder

Human USP1 & UAF1 Protein, GST Tag&Strep II Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.