Human USP1 & UAF1 Protein, GST Tag&Strep II Tag, Unconjugated, Insect 100 ug

Catalog Number: ABS-US1-H85W3-100UG
Article Name: Human USP1 & UAF1 Protein, GST Tag&Strep II Tag, Unconjugated, Insect 100 ug
Biozol Catalog Number: ABS-US1-H85W3-100UG
Supplier Catalog Number: US1-H85W3-100ug
Alternative Catalog Number: ABS-US1-H85W3-100UG
Manufacturer: AcroBiosystems
Host: Insect
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Unconjugated
USP1 (ubiquitin-specific protease 1) is a deubiquitinating enzyme crucial for DNA damage repair, cell cycle regulation, and protein homeostasis. Its catalytic efficiency is markedly enhanced by UAF1 (USP1-associated factor 1), a cofactor that stabilizes USP1 and directs it to nuclear substrates. Together, the USP1-UAF1 complex removes ubiquitin from key proteins such as PCNA and FANCD2, maintaining genomic stability and influencing cancer development, making it a potential therapeutic target in oncology. - Proteine/Peptide
Molecular Weight: 114.1 kDa & 77.8 kDa
Tag: N-GST | C-Strep II
NCBI: 94782
Buffer: 50 mM Tris, 150 mM NaCI, pH7.5
Purity: 95%
Form: Liquid
Target: USP1 & UAF1
Human USP1 & UAF1 Protein, GST Tag&Strep II Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.