Anti-Semaphorin-3A (C-terminal) Antibody, Rabbit, Polyclonal

Produktübersicht

• Artikelname: Anti-Semaphorin-3A (C-terminal) Antibody, Rabbit, Polyclonal
• Artikelnummer: ABT-AN1944
• Hersteller Artikelnummer: AN1944
• Alternativnummer: ABT-AN1944-100UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Alternative Synonym: Sema3A, Semaphorin III

Produktbeschreibung

One family of inhibitory axon guidance molecules is the semaphorins. The semaphorins include secreted, transmembrane, and GPI-anchored extracellular molecules that are involved in regulating axon guidance by inhibiting axons from growing toward incorrect targets. Semaphorin 3A (Sema3A) may play a particularly interesting role in limiting axon regeneration since it is expressed in meningeal fibroblasts that invade the injured spinal cord and surround the glial scar. In addition, the Sema3A co-receptors, Neuropilin-1 and Plexin-A1, are expressed on axons that regenerate up to the injured region, but do not cross this Sema3A-containing region. Thus, Sema3A and its co-receptors may have important roles in regulating axon guidance during neuronal development and after neuronal injury.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 88889
• NCBI: 10371
• UniProt: Q14563