Anti-Semaphorin-3A (C-terminal) Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AN1944
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| Article Name: | Anti-Semaphorin-3A (C-terminal) Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AN1944 |
| Supplier Catalog Number: | AN1944 |
| Alternative Catalog Number: | ABT-AN1944-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Alternative Names: | Sema3A, Semaphorin III |
| One family of inhibitory axon guidance molecules is the semaphorins. The semaphorins include secreted, transmembrane, and GPI-anchored extracellular molecules that are involved in regulating axon guidance by inhibiting axons from growing toward incorrect targets. Semaphorin 3A (Sema3A) may play a particularly interesting role in limiting axon regeneration since it is expressed in meningeal fibroblasts that invade the injured spinal cord and surround the glial scar. In addition, the Sema3A co-receptors, Neuropilin-1 and Plexin-A1, are expressed on axons that regenerate up to the injured region, but do not cross this Sema3A-containing region. Thus, Sema3A and its co-receptors may have important roles in regulating axon guidance during neuronal development and after neuronal injury. |
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