Anti-Beta-Defensin Antibody, Rabbit, Polyclonal

Produktübersicht

• Artikelname: Anti-Beta-Defensin Antibody, Rabbit, Polyclonal
• Artikelnummer: ABT-AN2090
• Hersteller Artikelnummer: AN2090
• Alternativnummer: ABT-AN2090-100UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Alternative Synonym: DEFB1, BD1, Defensin beta 1 preproprotein, HBD

Produktbeschreibung

A novel, nonhemolytic antimicrobial peptide (human beta-defensin-3, hBD-3) was isolated from human lesional psoriatic scales and cloned from keratinocytes. hBD-3 demonstrated a salt-insensitive broad spectrum of potent antimicrobial activity against many potentially pathogenic microbes including multiresistant S. aureus and vancomycin-resistant Enterococcus faecium. Keratinocytes and airway epithelial cells are cellular sources of hBD-3. Tumor necrosis factor alpha and contact with bacteria were found to induce hBD-3 mRNA expression. hBD-3 therefore might be important in the innate epithelial defense of infections by various microorganisms seen in skin and lung, such as cystic fibrosis.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 7420
• NCBI: 1672
• UniProt: P60022