Anti-TRAIL R2 (DR5) Antibody, Rabbit, Polyclonal

Produktübersicht

• Artikelname: Anti-TRAIL R2 (DR5) Antibody, Rabbit, Polyclonal
• Artikelnummer: ABT-AN2125
• Hersteller Artikelnummer: AN2125
• Alternativnummer: ABT-AN2125-100UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Alternative Synonym: TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9, UNQ160/PRO186

Produktbeschreibung

TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines. A distinct receptor for TRAIL, TRAIL-R2 (aka Death Receptor 5 (DR5)), by ligand-based affinity purification and subsequent molecular cloning. TRAIL-R2 is widely expressed and the gene encoding TRAIL-R2 is located on human chromosome 8p22-21. TRAIL-R2 engages a caspase-dependent apoptotic pathway but, in contrast to TRAIL-R1, TRAIL-R2 mediates apoptosis via the intracellular adaptor molecule FADD/MORT1.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 47878
• NCBI: 8795
• UniProt: O14763