Anti-RASSF1 (NORE1) Antibody, Rabbit, Polyclonal

Artikelnummer: ABT-AN2134
Artikelname: Anti-RASSF1 (NORE1) Antibody, Rabbit, Polyclonal
Artikelnummer: ABT-AN2134
Hersteller Artikelnummer: AN2134
Alternativnummer: ABT-AN2134-100UL
Hersteller: Abcepta
Wirt: Rabbit
Kategorie: Antikörper
Alternative Synonym: RASSF5, Ras association domain-containing protein 5, New ras effector 1, Regulator for cell adhesion and polarization enriched in lymphoid tissues, RAPL
RASSF1A, a new tumor-suppressor gene located at 3p21.3 is frequently inactivated by promoter region hypermethylation in a variety of human cancers including lung, breast, kidney and neuroblastoma. Another member of the RASSF1 gene family, Ras effector NORE1, which is structurally related to RASSF1, can also mediate a Ras-dependent apoptosis. Moreover, an analysis of NORE1 protein expression showed that it is frequently down-regulated in lung tumor cell lines and primary lung tumors.
Klonalität: Polyclonal
Molekulargewicht: 47090
NCBI: 83593
UniProt: Q8WWW0