Anti-RASSF1 (NORE1) Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AN2134
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| Article Name: | Anti-RASSF1 (NORE1) Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AN2134 |
| Supplier Catalog Number: | AN2134 |
| Alternative Catalog Number: | ABT-AN2134-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Alternative Names: | RASSF5, Ras association domain-containing protein 5, New ras effector 1, Regulator for cell adhesion and polarization enriched in lymphoid tissues, RAPL |
| RASSF1A, a new tumor-suppressor gene located at 3p21.3 is frequently inactivated by promoter region hypermethylation in a variety of human cancers including lung, breast, kidney and neuroblastoma. Another member of the RASSF1 gene family, Ras effector NORE1, which is structurally related to RASSF1, can also mediate a Ras-dependent apoptosis. Moreover, an analysis of NORE1 protein expression showed that it is frequently down-regulated in lung tumor cell lines and primary lung tumors. |
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