Anti-PRG3 Antibody, Rabbit, Polyclonal

Artikelnummer: ABT-AN2136
Artikelname: Anti-PRG3 Antibody, Rabbit, Polyclonal
Artikelnummer: ABT-AN2136
Hersteller Artikelnummer: AN2136
Alternativnummer: ABT-AN2136-100UL
Hersteller: Abcepta
Wirt: Rabbit
Kategorie: Antikörper
Alternative Synonym: Proteoglycan 3, Eosinophil major basic protein homolog, Prepro-major basic protein homolog, Prepro-MBPH
The p53 tumor suppressor protein induces cell cycle arrest or apoptosis in response to cellular stresses. PRG3 (p53-responsive gene 3), is induced specifically under p53-dependent apoptotic conditions in human colon cancer cells. PRG3 has significant homology to bacterial oxidoreductases and the apoptosis-inducing factor, AIF. Unlike AIF, PRG3 localizes in the cytoplasm and its ectopic expression induces apoptosis. The PRG3 gene is thus a novel p53 target gene in a p53-dependent apoptosis pathway
Klonalität: Polyclonal
Molekulargewicht: 25406
NCBI: 10394
UniProt: Q9Y2Y8