Androgen receptor, Clone: [R03657], Rabbit, Polyclonal

Produktübersicht

• Artikelname: Androgen receptor, Clone: [R03657], Rabbit, Polyclonal
• Artikelnummer: ABT-AP22418A-EV
• Hersteller Artikelnummer: AP22418a-ev
• Alternativnummer: ABT-AP22418A-EV-50UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Alternative Synonym: Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4, AR, DHTR, NR3C4

Produktbeschreibung

Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues (PubMed:19022849). Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation (PubMed:20812024). Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.

Produkteigenschaften

• Klonalität: Polyclonal
• Klon-Bezeichnung: [R03657]
• Molekulargewicht: 99188
• NCBI: 367
• UniProt: P10275
• Formulierung: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Target-Kategorie: This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human.