Androgen receptor, Clone: [R03657], Rabbit, Polyclonal

Product Overview

• Article Name: Androgen receptor, Clone: [R03657], Rabbit, Polyclonal
• Biozol Catalog Number: ABT-AP22418A-EV
• Supplier Catalog Number: AP22418a-ev
• Alternative Catalog Number: ABT-AP22418A-EV-50UL
• Manufacturer: Abcepta
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human
• Alternative Names: Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4, AR, DHTR, NR3C4

Product Description

Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues (PubMed:19022849). Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation (PubMed:20812024). Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.

Product Properties

• Clonality: Polyclonal
• Clone Designation: [R03657]
• Molecular Weight: 99188
• NCBI: 367
• UniProt: P10275
• Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Target: This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human.