LINGO-1 Antibody, Clone: [R03067], Rabbit, Polyclonal

Produktübersicht

• Artikelname: LINGO-1 Antibody, Clone: [R03067], Rabbit, Polyclonal
• Artikelnummer: ABT-AP22457A
• Hersteller Artikelnummer: AP22457a
• Alternativnummer: ABT-AP22457A-200UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Mouse
• Alternative Synonym: Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, Leucine-rich repeat and immunoglobulin domain-containing protein 1, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6A, LINGO1, LERN1, LRRN6A

Produktbeschreibung

Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity).

Produkteigenschaften

• Klonalität: Polyclonal
• Klon-Bezeichnung: [R03067]
• Molekulargewicht: 69876
• NCBI: 84894
• UniProt: Q96FE5
• Formulierung: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Target-Kategorie: This LINGO-1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human LINGO-1.