LINGO-1 Antibody, Clone: [R03067], Rabbit, Polyclonal

Product Overview

• Article Name: LINGO-1 Antibody, Clone: [R03067], Rabbit, Polyclonal
• Biozol Catalog Number: ABT-AP22457A
• Supplier Catalog Number: AP22457a
• Alternative Catalog Number: ABT-AP22457A-200UL
• Manufacturer: Abcepta
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Mouse
• Alternative Names: Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, Leucine-rich repeat and immunoglobulin domain-containing protein 1, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6A, LINGO1, LERN1, LRRN6A

Product Description

Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity).

Product Properties

• Clonality: Polyclonal
• Clone Designation: [R03067]
• Molecular Weight: 69876
• NCBI: 84894
• UniProt: Q96FE5
• Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Target: This LINGO-1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human LINGO-1.