DNA Ligase 4 Antibody, Rabbit, Polyclonal

Produktübersicht

• Artikelname: DNA Ligase 4 Antibody, Rabbit, Polyclonal
• Artikelnummer: ABT-AP51318
• Hersteller Artikelnummer: AP51318
• Alternativnummer: ABT-AP51318-100UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, ICC, IHC-P, WB
• Spezies Reaktivität: Human
• Alternative Synonym: DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4, LIG4

Produktbeschreibung

Efficiently joins single-strand breaks in a double- stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA- dependent protein kinase complex DNA-PK to these DNA ends.

Produkteigenschaften

• Klonalität: Polyclonal
• NCBI: 3981
• UniProt: P49917