DNA Ligase 4 Antibody, Rabbit, Polyclonal

Product Overview

• Article Name: DNA Ligase 4 Antibody, Rabbit, Polyclonal
• Biozol Catalog Number: ABT-AP51318
• Supplier Catalog Number: AP51318
• Alternative Catalog Number: ABT-AP51318-100UL
• Manufacturer: Abcepta
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, ICC, IHC-P, WB
• Species Reactivity: Human
• Alternative Names: DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4, LIG4

Product Description

Efficiently joins single-strand breaks in a double- stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA- dependent protein kinase complex DNA-PK to these DNA ends.

Product Properties

• Clonality: Polyclonal
• NCBI: 3981
• UniProt: P49917