CDC46 Antibody, Rabbit, Polyclonal

Artikelnummer: ABT-AP51338
Artikelname: CDC46 Antibody, Rabbit, Polyclonal
Artikelnummer: ABT-AP51338
Hersteller Artikelnummer: AP51338
Alternativnummer: ABT-AP51338-100UL
Hersteller: Abcepta
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, ICC, IHC-P, WB
Spezies Reaktivität: Human, Mouse, Rat
Alternative Synonym: DNA replication licensing factor MCM5, CDC46 homolog, P1-CDC46, MCM5, CDC46
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for once per cell cycle DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP.
Klonalität: Polyclonal
NCBI: 4174
UniProt: P33992