CDC46 Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP51338
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| Article Name: | CDC46 Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP51338 |
| Supplier Catalog Number: | AP51338 |
| Alternative Catalog Number: | ABT-AP51338-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, ICC, IHC-P, WB |
| Species Reactivity: | Human, Mouse, Rat |
| Alternative Names: | DNA replication licensing factor MCM5, CDC46 homolog, P1-CDC46, MCM5, CDC46 |
| Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for once per cell cycle DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP. |
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