Patched Antibody, Rabbit, Polyclonal

Produktübersicht

• Artikelname: Patched Antibody, Rabbit, Polyclonal
• Artikelnummer: ABT-AP51457
• Hersteller Artikelnummer: AP51457
• Alternativnummer: ABT-AP51457-100UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human, Mouse, Rat
• Alternative Synonym: Protein patched homolog 1, PTC, PTC1, PTCH1, PTCH

Produktbeschreibung

Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehogs proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.

Produkteigenschaften

• Klonalität: Polyclonal
• NCBI: 5727
• UniProt: Q13635