Patched Antibody, Rabbit, Polyclonal

Catalog Number: ABT-AP51457
Article Name: Patched Antibody, Rabbit, Polyclonal
Biozol Catalog Number: ABT-AP51457
Supplier Catalog Number: AP51457
Alternative Catalog Number: ABT-AP51457-100UL
Manufacturer: Abcepta
Host: Rabbit
Category: Antikörper
Application: WB
Species Reactivity: Human, Mouse, Rat
Alternative Names: Protein patched homolog 1, PTC, PTC1, PTCH1, PTCH
Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehogs proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
Clonality: Polyclonal
NCBI: 5727
UniProt: Q13635