URI1 Antibody, Rabbit, Polyclonal

Produktübersicht

• Artikelname: URI1 Antibody, Rabbit, Polyclonal
• Artikelnummer: ABT-AP51846
• Hersteller Artikelnummer: AP51846
• Alternativnummer: ABT-AP51846-100UL
• Hersteller: Abcepta
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Alternative Synonym: Unconventional prefoldin RPB5 interactor 1, Protein NNX3, Protein phosphatase 1 regulatory subunit 19, RNA polymerase II subunit 5-mediating protein, RPB5-mediating protein, URI1, C19orf2, NNX3, PPP1R19, RMP, URI

Produktbeschreibung

Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region. Antagonizes transcriptional modulation via hepatitis B virus X protein.

Produkteigenschaften

• Klonalität: Polyclonal
• NCBI: 8725
• UniProt: O94763