URI1 Antibody, Rabbit, Polyclonal

Product Overview

• Article Name: URI1 Antibody, Rabbit, Polyclonal
• Biozol Catalog Number: ABT-AP51846
• Supplier Catalog Number: AP51846
• Alternative Catalog Number: ABT-AP51846-100UL
• Manufacturer: Abcepta
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human, Mouse, Rat
• Alternative Names: Unconventional prefoldin RPB5 interactor 1, Protein NNX3, Protein phosphatase 1 regulatory subunit 19, RNA polymerase II subunit 5-mediating protein, RPB5-mediating protein, URI1, C19orf2, NNX3, PPP1R19, RMP, URI

Product Description

Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region. Antagonizes transcriptional modulation via hepatitis B virus X protein.

Product Properties

• Clonality: Polyclonal
• NCBI: 8725
• UniProt: O94763