LFNG Antibody (Center) Blocking Peptide

Artikelnummer: ABT-BP9524C
Artikelname: LFNG Antibody (Center) Blocking Peptide
Artikelnummer: ABT-BP9524C
Hersteller Artikelnummer: BP9524c
Alternativnummer: ABT-BP9524C-500UG
Hersteller: Abcepta
Kategorie: Proteine/Peptide
Alternative Synonym: Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, LFNG
LFNG belongs to evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This protein is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150).
NCBI: 3955
UniProt: Q8NES3
Formulierung: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.